Title

·         30 years experience in early drug discovery at large and small pharma

·         Created Molecular Pharmacology lab at start-up company

·         Managed department that developed assays for new targets, performed high-throughput screening, supported medicinal chemistry  

Specific Areas of Expertise

• GPCR pharmacology
• Evaluation of new molecular targets for drug discovery
• Development and validation of screening assays for drug discovery
• Pharmacological support of hit-to-lead and lead optimization chemistry
• Ability to drive exploratory research projects forward while focused on successful drug discovery
• Authoring and editing of scientific manuscripts, research proposals, grant proposals, and preclinical portions of regulatory documents
• Managing outsourcing of pharmacological testing
• Preparation of Radioactive Materials License application
• Preparation of documents required by local government to permit laboratory occupancy

Publications and Memberships

·         >60 Publications

·         Member of Society for Neuroscience, American Society for Pharmacology and Experimental Therapeutics, American Medical Writers Association, ChemPharma Professional Association, Pharmaceutical Consulting Consortium, Inc., Greater Philadelphia Senior Executives Group

Positions                          

·         Director, Molecular Pharmacology                                           Adolor

·         Laboratory Head, Enzymology                                                    Sterling-Winthrop

·         Staff Scientist, Dept of Inflammation                                      Merck

·         Laboratory Scientist, Dept Pharmacology                              JHU Sch of Med